Link - LoZ titles were amazing, and I've played Link to the Past, Minish Cap and Ocarina of time and the expexperience of these games were just out of the world. Planning to play Majora's Mask as soon as it comes out for the 3ds. Playing as a quiet character who just shuts up and does everything he's told is one of the best experiences of playing a game.
Megaman (Starforce's Geo) - Playing as a character who becomes a wave for is a good series on its own. Nintendo made it to be a completely separate game from the original storyline, but the game was awesome, and along with Geo and his tragic story, the game gets better.
Isaac - Golden Sun 1's main protagonist was an amazing character to play as. The story starts off with an eerie and creepy feeling, but as you play, you start to enjoy that feeling. Playing as a character who doesn't speak even a single word in the game was amazing as you can make all the yes or no decisions for him, giving you the illusion of you doing and being responsible for everything that's happening. When he reappears in the second game, you get struck with joy because he can speak, and seeing him in the final game, when he's around the age of 40 is just overwhelming.