I like them both o.o
Harvest moon for days I just want to relax and farm and just have fun ..
Cute graphics most of the time ..mild story easy to play most of the time..
(I have Harvest Moon Lost Valley, New Beginning & Tale of two towns)
Rune factory for days I wanna kick some butt and fight while side tracking with some farm maybe small side things..
More realistic less cute graphics, intense story's in my opinion more challenging to play )
(I have Wii Runefactory Tides of Destiny )
Both games are great!